»Ê¹Ú²ÊƱ

Healthier lifespans

Personalise
WILD - Macquarie Fields Men’s Shed research imapct statement

The goal of achieving healthier lifespans is one of our most ambitious and requires a high level of collaboration between researchers, clinicians, medical institutions and lawmakers. »Ê¹Ú²ÊƱ leads translational practice in Australia, and around the world, to improve quality of life, care and outcomes for individual patients and society as a whole.

Life – with all its complexity, joy and heartbreak - is what motivates us to build a better world. We believe that to improve health, we must understand the human experience, the forces that affect wellbeing, and the way policies and services converge to address community needs. »Ê¹Ú²ÊƱ places a strong emphasis on public health and epidemiology, from harm reduction and disease prevention to vaccine efficacy and therapeutics. We engage in bold projects, like the international effort to eliminate cervical cancer in the Pacific, and practise tenderness to improve individual treatment of mental health, substance disorders and end-of-life-care.

We’ve made a bet on precision medicine, which is already revolutionising healthcare by allowing us to tailor diagnostics and treatments to a patient’s unique epigenetic profile. Through the use of AI-driven computer sequencing we can now decode vast amounts of gene, RNA and protein data from patient and disease cells. This detailed understanding allows us to better predict risk, progression and treatment response – leading to huge advances in treatment plans that optimise therapeutic efficacy while minimising adverse effects.

Most importantly, we're accelerating the translation of research into publicly available healthcare. Our researchers have developed wearable technologies to prevent falls in older adults, made medical history with Australia’s first successful childbirth from a transplanted uterus, and partnered in the nation’s largest childhood cancer initiative, . This groundbreaking trial guarantees personalised care to every child with high-risk cancer and has already shown significant improvement in progression-free survival. When it comes to health, »Ê¹Ú²ÊƱ is committed to going big.

Areas of expertise

The below strengths represent a snapshot of our expertise but are by no means an exhaustive list. If you have a specific research area of interest or project that is not represented here, please get in touch so that we can find an expert(s) to best match your needs.

Students studying Biomedicine in labs
Infectious disease
»Ê¹Ú²ÊƱ has strengths in epidemiology and the prevention of infectious diseases, including epidemics, pandemics, tropical diseases and emerging infections. We integrate clinical studies with computational models, genomics and machine learning to enhance vaccine efficacy and immunotherapies. Our research takes a holistic view of the health system and evaluates the effectiveness of clinical care and public health policy among vulnerable populations, particularly with regards to viral hepatitis, HIV and STIs.
NDRG1 (Green) and ALIX (Red) localization in pancreatic cancer cells
Cancer
Our research aims to improve outcomes for people at each stage of the cancer journey – from prevention through to treatment, survivorship support and palliative care. This requires consideration of the whole person, including their epigenetics, mental health and interactions with the health system. Our multidisciplinary approach involves collaboration between a team of experts. Nanotechnologists create synthetic biologic materials, while biologists map 3D genome architecture. Clinicians then translate these scientific discoveries into diagnostics and tailored therapeutics which bypass mechanisms of resistance and lead to better patient outcomes.
Female scientist at RNA Institute
Precision medicine & genomics
From the microbiome to the metagenome, »Ê¹Ú²ÊƱ is accelerating personalised medicine. Our research into synthetic biology and multiomic data analysis is used to create precision diagnostics and treatments. We develop nanoscale sensing and imaging tools to measure cellular function and apply AI-powered data science to drive the next-generation of genomic sequencing and transcriptomics. This work has led to huge advances in targeted drug delivery, tissue repair, and regenerative medicines such as CRISPR-cas gene therapy and stem cell treatment.
A pen points to a region of a brain scan on a computer monitor
Neuroscience, mental health & addiction
We’re evolving the science of how the brain works using advanced imaging and functional genomic studies in human brain tissue and neuronal cell culture systems. An improved understanding of these processes will inform diagnosis and treatment of mental illness and substance disorders. We’re also exploring a range of interventions – from virtual reality environments to cognitive behavioural therapy, hypnosis, mindfulness and pharmacology. Our expertise includes anxiety, depression, post-traumatic stress, child and youth mental health, and suicide prevention.
Community day »Ê¹Ú²ÊƱ Kensington
Public health & future health systems
We translate evidence into practice to improve health policy, services and programs. This starts with an understanding of the socioeconomic, cultural and political determinants of health and how to best deliver services that address community needs. Our research spans integrated services delivery for children and families, from the effects nutrition on metabolic health to the prevention of infectious disease among people with disabilities, drug users, sex workers and other vulnerable populations.

»Ê¹Ú²ÊƱ Future Health

In 2024, »Ê¹Ú²ÊƱ hosted theÌýFutures Expo Series to showcase research aligned with theÌýÌýpriority areas. The events brought together businesses, investors, and government to explore collaboration opportunities with our leading innovation community.

Missed the series? Don’t worry. You can dive into the insights and opportunities captured in our themed Futures Expo booklets.

Ìý

Ìý