
Dr Iman Roohani
(B.Sc. Mater Sci, M.Sc. Biomat Sci, Ph.D. Biomed Eng),
Biographical Details
I was awarded my Ph.D. degree in 2014 (in Biomedical Engineering, Biomaterials and Tissue Engineering) from University of Sydney. My research group is investigating cell-biomaterial based strategies for musculoskeletal tissue regeneration and their application in the clinical translation of orthopaedic medical devices. This research technology platform involves 3D Biofabrication and additive manufacturing of biomaterials and medical devices applied to regenerative medicine of bone and development of novel nanocarriers and bone grafts to promote bone healing or treat bone diseases. Throughout my career, I have developed several novel biomaterials for the treatment of large bone defects, osteochondral defect regeneration and for stabilisation of metallic implants. I was fortunate as an early career researcher and the main inventor, to translate an innovative bioengineering technology from the laboratory bench through to successful commercialisation of a tissue engineering product. This product, a novel synthetic bone graft, Sr-HT-Gahnite, has been exclusively licenced globally by an Australian orthopaedic medical device company, Allegra Orthopaedics. Allegra was awarded $1.6M from the NSW Government Medical Devices Fund in 2015 to bring this technology to market. My achievements have been recognised through receiving of the Australian National Health and Medical Research Council (NHMRC) Early Career Fellowship for funding in 2016–2019.In 2017, I moved to University of New South Wales, School of Chemistry as a research fellow to work closely with Scientia Professor Justin Gooding and establish a Biomaterials Design and Tissue Engineering lab.
Available projects
- Cell-instructive and cell-responsive biomaterials (the aim is to develop a unique approach in building biomaterials that are cell-instructive and cell-responsive. This can create a selective and dynamic feedback loop between a cell and the microenvironment).
- Gene activating scaffolds (The aim of this study is to develop a new generation of 3D constructs that can host cells in a 3D dimensional environment and are able to deliver biomolecules into the cells).
- New generation of bioceramic, bioactive glasses and bone cements for musculoskeletal tissue regeneration.
- Development of universal methodologies to test efficacy of biomaterials; replacing the conventional methods.
- Printing complexed shaped inorganic based tissue scaffolds for tissue engineering applications.
- Synthesis of new generation of bioceramic, bioactive glasses and bone cements for musculoskeletal tissue regeneration.
- Development of biomaterials as synthetic tendon, skin and treatment of cardiovascular disease.
- Biomaterials for neural regeneration (material effects on cell behaviours such as proliferation, differentiation, directed neurite growth, and tissue function).
- An exhaustive investigation on Biomaterials-microstructure-protein/cell interactions.
- Surface coating strategies for medical implants and tissue scaffolds.
- Designing load bearing scaffolds for treatment of segmental bone defects.
- Synthesis and fabrication of multifunctional calcium phosphate nanoparticles.
Interested in joining the group?
Please contact me
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