Dr Muhammad Yasir

Senior Research Associate

PhD in Medical Microbiology ( University of New South Wales, Sydney, Australia, 2020)

MPhil in Microbiology (Quaid-e-Azam University, Islamabad, Pakistan, 2013)

Medicine & Health

School of Optometry and Vision Science

My research focuses on investigating the mechanisms of action of newly designed antimicrobial peptides and peptidomimetics.�� These new antimicrobials are able to kill many different types of microbes including bacteria, fungi, and viruses. I am particularly interested in how these new antimicrobials prevent microbes from colonizing surfaces. My research has applications for preventing the transmission of disease and reducing the incidence of hospital-acquired infections.

E-mail

m.yasir@unsw.edu.au

Journal articles | 2025

Bahatheg G; Kuppusamy R; Yasir M; Mishra SK; Black DSC; Willcox M; Kumar N, 2025, 'Functionalized Phenyl Peptoids with Enhanced Antibacterial Potency', ACS Infectious Diseases, 11, pp. 1648 - 1661,

Journal articles | 2025

Maulvi FA; Sahu A; Ren X; Desai DT; Kalaiselvan P; Yasir MA; Kuppusamy R; Shah DO; Willcox MDP, 2025, 'Mel4-coated hyaluronic acid-laden etafilcon A contact lenses: Improved wettability with retained antimicrobial properties', International Journal of Biological Macromolecules, 304,

Journal articles | 2025

Mishra SK; Yasir M; Kuppusamy R; Wong EHH; Hui A; Sørensen K; Lin JS; Jenssen H; Barron AE; Willcox M, 2025, 'Antimicrobial activity of peptoids against Metallo-β-lactamase-producing Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and other WHO priority pathogens, including Candida auris', Journal of Applied Microbiology, 136,

Journal articles | 2025

Shen J; Yasir M; Willcox M, 2025, 'Staphylococcal exotoxins in ocular infection with focus on enterotoxins', Microbiological Research, 299,

Journal articles | 2025

Shen J; Yasir M; Willcox M, 2025, 'Whole genome sequencing-based prediction of antibiotic-resistance of ocular Staphylococcus aureus across six continents', Experimental Eye Research, 257,

Journal articles | 2025

Yasir M; Willcox MDP; Ings J; Bruinessen PV, 2025, 'Control of Aerosolised Type A Influenza Virus H1N1 and a Coronavirus with Vapours Containing Catmint Essential Oil', Hygiene, 5,

Journal articles | 2024

Bahatheg G; Kuppusamy R; Yasir M; Bridge S; Mishra SK; Cranfield CG; StC. Black D; Willcox M; Kumar N, 2024, 'Dimeric peptoids as antibacterial agents', Bioorganic Chemistry, 147,

Journal articles | 2024

Hassan M; Shahzadi S; Yasir M; Chun W; Kloczkowski A, 2024, 'Therapeutic Implication of miRNAs as an Active Regulatory Player in the Management of Pain: A Review', GENES, 15,

Journal articles | 2024

Hassan M; Yasir M; Shahzadi S; Chun W; Kloczkowski A, 2024, 'Molecular Role of Protein Phosphatases in Alzheimer's and Other Neurodegenerative Diseases', BIOMEDICINES, 12,

Journal articles | 2024

Hong Z; Yu TT; Yasir M; Sara M; Black DSC; Willcox MDP; Kuppusamy R; Kumar N, 2024, 'Daidzein-Based Amphiphilic Small Molecular Antimicrobial Peptidomimetics as Novel Antimicrobial Agents with Anti-Biofilm Activity', Chemistryselect, 9,

Journal articles | 2024

Kruse HV; Chakraborty S; Chen R; Kumar N; Yasir M; Lewin WT; Suchowerska N; Willcox MDP; McKenzie DR, 2024, 'Protecting Orthopaedic Implants from Infection: Antimicrobial Peptide Mel4 Is Non-Toxic to Bone Cells and Reduces Bacterial Colonisation When Bound to Plasma Ion-Implanted 3D-Printed PAEK Polymers', Cells, 13, pp. 656,

Journal articles | 2024

Sara M; Hui A; Yasir M; Peguda HK; Kalaiselvan P; Willcox M, 2024, 'Intrastromal Corneal Ring Implants Associated Bacterial Infections', Current Eye Research, 49, pp. 1012 - 1020,

Journal articles | 2024

Sara M; Yasir M; Kalaiselvan P; Hui A; Kuppusamy R; Kumar N; Chakraborty S; Yu TT; Wong EHH; Molchanova N; Jenssen H; Lin JS; Barron AE; Willcox M, 2024, 'The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens', Contact Lens and Anterior Eye, 47,

Journal articles | 2024

Yasir M; Park J; Chun W, 2024, 'Discovery of Novel Aldose Reductase Inhibitors via the Integration of Ligand-Based and Structure-Based Virtual Screening with Experimental Validation', ACS OMEGA, 9, pp. 20338 - 20349,

Journal articles | 2024

Yasir M; Park J; Han E-T; Han J-H; Park WS; Chun W, 2024, 'Identification of Malaria-Selective Proteasome β5 Inhibitors Through Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25,

Journal articles | 2024

Yasir M; Park J; Han E-T; Han J-H; Park WS; Chun W, 2024, 'Investigating the Inhibitory Potential of Flavonoids against Aldose Reductase: Insights from Molecular Docking, Dynamics Simulations, and gmx_MMPBSA Analysis', CURRENT ISSUES IN MOLECULAR BIOLOGY, 46, pp. 11503 - 11518,

Journal articles | 2024

Yasir M; Park J; Han E-T; Park WS; Han J-H; Chun W, 2024, 'Drug Repositioning via Graph Neural Networks: Identifying Novel JAK2 Inhibitors from FDA-Approved Drugs through Molecular Docking and Biological Validation', MOLECULES, 29,

Journal articles | 2024

Yasir M; Park J; Han E-T; Park WS; Han J-H; Chun W, 2024, 'Identification of Potential Tryptase Inhibitors from FDA-Approved Drugs Using Machine Learning, Molecular Docking, and Experimental Validation', ACS OMEGA, 9, pp. 38820 - 38831,

Journal articles | 2024

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2024, 'Virtual Screening of Flavonoids against Plasmodium vivax Duffy Binding Protein Utilizing Molecular Docking and Molecular Dynamic Simulation', CURRENT COMPUTER-AIDED DRUG DESIGN, 20, pp. 616 - 627,

Journal articles | 2024

Yasir M; Willcox MDP, 2024, 'The use of ultraviolet light generated from light-emitting diodes for the disinfection of transvaginal ultrasound probes', Plos One, 19, pp. e0298449,

Journal articles | 2023

Hassan M; Shahzadi S; Malik A; ud Din S; Yasir M; Chun W; Kloczkowski A, 2023, 'Oncomeric Profiles of microRNAs as New Therapeutic Targets for Treatment of Ewing's Sarcoma: A Composite Review', GENES, 14,

Journal articles | 2023

Hassan M; Shahzadi S; Yasir M; Chun W; Kloczkowski A, 2023, 'Computational prognostic evaluation of Alzheimer's drugs from FDA-approved database through structural conformational dynamics and drug repositioning approaches', SCIENTIFIC REPORTS, 13,

Journal articles | 2023

Kalaiselvan P; Yasir M; Vijay AK; Willcox MDP; Tummanapalli S, 2023, 'Longevity of hand sanitisers on fingers', Clinical and Experimental Optometry, 106, pp. 436 - 442,

Journal articles | 2023

Kuppusamy R; Yasir M; Yu TT; Voli F; Vittorio O; Miller MJ; Lewis P; Black DSC; Willcox M; Kumar N, 2023, 'Tuning the Anthranilamide Peptidomimetic Design to Selectively Target Planktonic Bacteria and Biofilm', Antibiotics, 12, pp. 585,

Journal articles | 2023

Mishra SK; Yasir M; Willcox M; Mishra Baishnab SK, 2023, 'Candida auris: an emerging antimicrobial-resistant organism with the highest level of concern', Lancet Microbe, 4, pp. e482 - e483,

Journal articles | 2023

Willcox MDP; Bahatheg G; Carnt N; Kalaiselvan P; Kumar N; Kuppusamy R; Rayamajhee B; Sara M; Stapleton F; Vijay AK; Yasir M; Yu TT, 2023, 'Biofilms and contact lenses: problems and solutions', Microbiology Australia, 44, pp. 96 - 99,

Journal articles | 2023

Yasir M; Park J; Chun W, 2023, 'EWS/FLI1 Characterization, Activation, Repression, Target Genes and Therapeutic Opportunities in Ewing Sarcoma', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2023, 'Computational Exploration of Licorice for Lead Compounds against Plasmodium vivax Duffy Binding Protein Utilizing Molecular Docking and Molecular Dynamic Simulation', MOLECULES, 28,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2023, 'Computational Exploration of the Effects of Mutations on GABA Aminotransferase in GABA Aminotransferase Deficiency', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2023, 'Machine Learning-Based Drug Repositioning of Novel Janus Kinase 2 Inhibitors Utilizing Molecular Docking and Molecular Dynamic Simulation', JOURNAL OF CHEMICAL INFORMATION AND MODELING, 63, pp. 6487 - 6500,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2023, 'Vismodegib Identified as a Novel COX-2 Inhibitor via Deep-Learning-Based Drug Repositioning and Molecular Docking Analysis', ACS OMEGA, 8, pp. 34160 - 34170,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Hassan M; Kloczkowski A; Chun W, 2023, 'Exploration of Flavonoids as Lead Compounds against Ewing Sarcoma through Molecular Docking, Pharmacogenomics Analysis, and Molecular Dynamics Simulations', MOLECULES, 28,

Journal articles | 2023

Yasir M; Park J; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Hassan M; Kloczkowski A; Chun W, 2023, 'Investigation of Flavonoid Scaffolds as DAX1 Inhibitors against Ewing Sarcoma through Pharmacoinformatic and Dynamic Simulation Studies', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24,

Journal articles | 2023

Yasir M; Park J; Lee Y; Han E-T; Park WS; Han J-H; Kwon Y-S; Lee H-J; Chun W, 2023, 'Discovery of GABA Aminotransferase Inhibitors via Molecular Docking, Molecular Dynamic Simulation, and Biological Evaluation', INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24,

Journal articles | 2022

Bahatheg G; Kuppusamy R; Yasir M; Black DSC; Willcox M; Kumar N, 2022, 'Short Tryptamine-Based Peptoids as Potential Therapeutics for Microbial Keratitis: Structure-Function Correlation Studies', Antibiotics, 11, pp. 1074,

Journal articles | 2022

Cometta S; Jones RT; Juárez-Saldivar A; Donose BC; Yasir M; Bock N; Dargaville TR; Bertling K; Brünig M; Rakić AD; Willcox M; Hutmacher DW, 2022, 'Melimine-Modified 3D-Printed Polycaprolactone Scaffolds for the Prevention of Biofilm-Related Biomaterial Infections', ACS Nano, 16, pp. 16497 - 16512,

Journal articles | 2022

Hassan M; Yasir M; Shahzadi S; Kloczkowski A, 2022, 'Exploration of Potential Ewing Sarcoma Drugs from FDA-Approved Pharmaceuticals through Computational Drug Repositioning, Pharmacogenomics, Molecular Docking, and MD Simulation Studies', ACS OMEGA, 7, pp. 19243 - 19260,

Journal articles | 2022

Kalaiselvan P; Yasir M; Kuppusamy R; Willcox M; Vijay AK, 2022, 'Ability of Essential Oil Vapours to Reduce Numbers of Culturable Aerosolised Coronavirus, Bacteria and Fungi', Antibiotics, 11, pp. 393,

Journal articles | 2022

Khan HA; Yasir M; Castel A, 2022, 'Performance of cementitious and alkali-activated mortars exposed to laboratory simulated microbially induced corrosion test', Cement and Concrete Composites, 128,

Journal articles | 2022

Khosravanihaghighi A; Koshy P; Yasir M; Romanazzo S; Lovric V; Kilian KA; Willcox MD; Walsh WR; Sorrell CC, 2022, 'Production of Antibacterial Activity and Bone Cell Proliferation by Surface Engineering of Ga- or Mn-Doped Ceria-Coated Biomedical Titanium Alloy', Advanced Engineering Materials, 24,

Journal articles | 2022

Magar LB; Rayamajhee B; Khadka S; Karki G; Thapa A; Yasir M; Thapa S; Panta OP; Sharma S; Poudel P, 2022, 'Detection of Bacillus Species with Arsenic Resistance and Plant Growth Promoting Efficacy from Agricultural Soils of Nepal', Scientifica, 2022,

Journal articles | 2022

Yasir M; Kumar Vijay A; Willcox M; Vijay A, 2022, 'Antiviral effect of multipurpose contact lens disinfecting solutions against coronavirus', Contact Lens and Anterior Eye, 45, pp. 101513,

Journal articles | 2022

Yasir M; Nawaz A; Ghazanfar S; Okla MK; Chaudhary A; Al WH; Ajmal MN; AbdElgawad H; Ahmad Z; Abbas F; Wadood A; Manzoor Z; Akhtar N; Din M; Hameed Y; Imran M, 2022, 'Anti-bacterial activity of essential oils against multidrug-resistant foodborne pathogens isolated from raw milk.', Braz J Biol, 84, pp. e259449,

Journal articles | 2021

Bhattacharjee S; Joshi R; Chughtai A; Heslop D; Wilcox M; MacIntyre R, 2021, 'Graphene and nanoparticles coated antimicrobial and biocompatible cotton/silk fabrics for protective clothing', ACS Applied Bio Materials

Journal articles | 2021

Din M; Babar KM; Shah D; Sarwar G; Khan S; Sadaf H; Ahmed SS; Ali FL; Yasir M; Ahmed N, 2021, 'Dissemination of NDM-1 in pseudomonas aeruginosa and klebsiella pneumoniae isolated from pus samples in tertiary care hospitals of Quetta, Pakistan', Journal of the Pakistan Medical Association, 71, pp. 228 - 232,

Journal articles | 2021

Yasir M; Dutta D; Willcox MDP, 2021, 'Enhancement of Antibiofilm Activity of Ciprofloxacin against Staphylococcus aureus by Administration of Antimicrobial Peptides'

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